Abstract:Aiming at the problem that there isn’t any standardized calibration method for the performance index of surface plasmon resonance (SPR) sensor, the calibration method for key performance indices of SPR sensor is summarized and proposed based on the comparison of relative methods and definition of each index. Experimental data of sucrose solutions with various concentrations are obtained by the self-building SPR instrument, and then the calibration method is used to determine the performance indices, such as noise, drift, sensitivity, resolution, linearity, dynamic range and reproducibility. Experimental results show that the definition of indices is reasonable, and the calibration method is correct, which has great significance for performance evaluation of SPR sensor.